Which is the most important strain in the pathogenesis of ventilator-induced lung injury
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Pathogenesis of ventilator-induced lung injury: trials and tribulations.
RESEARCH INTO VENTILATOR-INDUCED LUNG INJURY (VILI) spans the decades since this life-sustaining technology was introduced into widespread clinical use in the mid-twentieth century (24). Early on, it was recognized that lungs ventilated with high ventilatory pressures have a propensity to develop air leaks (barotrauma). However, investigators soon realized that it was excessive lung volume (vol...
متن کاملVentilator-induced lung injury.
From the Keenan Research Center, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, and the Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto — both in Toronto (A.S.S.); and Dipartimento di Anestesia e Medicina degli Stati Critici, Ospedale S. Giovanni Battista Molinette, Università di Torino, Turin, Italy (V.M.R.). Address reprint requ...
متن کاملVentilator-induced lung injury.
Severe physical-trauma can lead to the development of acute respiratory distress syndrome (ARDS). Currently, the only known treatment for ARDS is mechanical ventilation. However, if mechanical ventilation is applied inappropriately further injury and malfunction of the lungs may occur, and thus, causing a ventilator induced lung injury (VILI). VILI has several manifestations including volutraum...
متن کاملVentilator-induced lung injury.
The clinical relevance of experimental ventilator-induced lung injury has recently received a resounding illustration by the Acute Respiratory Distress Syndrome Network trial that showed a 22% reduction of mortality in patients with acute respiratory disease syndrome when lung mechanical stress was lessened by tidal volume reduction during mechanical ventilation. This clinical confirmation of t...
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ژورنال
عنوان ژورنال: Current Opinion in Critical Care
سال: 2014
ISSN: 1070-5295
DOI: 10.1097/mcc.0000000000000047